C4d/C4b standard for quantitative flow cytometry of humoral transplant rejection
US8383410B2 · kind B2 · utility
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29Claims
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Key dates
| Filing date | Mar 30, 2007 |
| Grant date | Feb 26, 2013 |
| Priority date | — |
| Expiry date | Apr 15, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/13
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention concerns an internal standard used to quantitative analysis of the risk of humoral (i.e. vascular) transplant rejection. The internal standard consists of a stable composition of the C4d complement bound to a carrier consisting of erythrocytes or microparticles. The invention also concerns a method for analyzing in vitro the risk of humoral organ transplant rejection, which consists in determining the amount of component of C4d component fixed on the erythrocytes contained in a blood sample from a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.