HCV inhibiting macrocyclic phenylcarbamates

US8383584B2 · kind B2 · utility

Assignees

• MEDIVIR AB · SE
• Janssen R & D Ireland · IE

Inventors

• Dmitry Antonov · Huddinge, SE
• Susana Ayesa Alvarez · Huddinge, SE
• Anna Karin Gertrud Linnea Belfrage · Huddinge, SE
• Carl Erik Daniel Jonsson · Huddinge, SE
• David Craig McGowan · Vilvoorde, BE
• Karl Magnus Nilsson · Vimmerby, SE
• Pierre Jean-Marie Bernard Raboisson · Sligo, IE
• Asa Annica Kristina Rosenquist · Huddinge, SE
• Bengt Bertil Samuelsson · Skärholmen, SE

Key dates

• Filing date: Feb 8, 2008
• Grant date: Feb 26, 2013
• Expiry date: Nov 5, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula I:including a stereoisomer thereof, or an N-oxide, a pharmaceutically acceptable addition salt, or a pharmaceutically acceptable addition solvate thereof; useful as HCV inhibitors; processes for preparing these compounds as well as pharmaceutical compositions comprising these compounds as active ingredient.