Patent · US Active

Aryl isoxazole compounds with antitumoural activities

US8383616B2 · kind B2 · utility

1Cited by

0References

16Claims

0Family size

Assignee

SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. · IT

Inventors

Giuseppe Giannini · Pomezia, IT
Walter Cabri · Sant Celoni, ES
Daniele Simoni · Ferrara, IT
Riccardo Baruchello · Ferrara, IT
Paolo Carminati · Pomezia, IT
Claudio Pisano · Aprilia, IT

Key dates

Filing date	Jun 30, 2009
Grant date	Feb 26, 2013
Priority date	—
Expiry date	Jun 30, 2029

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to formula I compounds having antitumoural activities through, as one possible biological target, the molecular chaperone heat shock protein 90 (Hsp90) inhibition. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of Hsp90 is responsive, and the pharmaceutical compositions containing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.