Patent · US Active

Collectin fusion proteins comprising TNF or trail

US8383774B2 · kind B2 · utility

7Cited by

0References

29Claims

0Family size

Assignee

APOGENIX AG · DE

Inventors

Oliver Hill · Neckarsteinach, DE
Christian Gieffers · Dossenheim, DE
Meinolf Thiemann · Schriesheim, DE
Marcus Branschädel · Heidelberg, DE

Key dates

Filing date	Jul 10, 2008
Grant date	Feb 26, 2013
Priority date	—
Expiry date	Dec 25, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/70
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention refers to a fusion protein comprising a TNF-superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.