Conformation-selective nucleic acid inhibitors of AMPA glutamate receptors
US8383794B2 · kind B2 · utility
1Cited by
0References
18Claims
0Family size
Inventors
Key dates
| Filing date | Oct 8, 2010 |
| Grant date | Feb 26, 2013 |
| Priority date | — |
| Expiry date | Nov 13, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/70571
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel nucleic acid ligands or aptamers that demonstrate potent and selective inhibition of the open-channel conformation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.