Patent · US Active

In vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging

US8388936B2 · kind B2 · utility

0Cited by

3References

2Claims

0Family size

Assignee

MCW Research Foundation, Inc. · US

Inventors

Balaraman Kalyanaraman · Wauwatosa, US
Joy Joseph · New Berlin, US
Kathleen Marie Schmainda · Wauwatosa, US
Douglas Edward Prah · Milwaukee, US
Marcos Lopez · Wauwatosa, US
Micael J. Hardy · Nîmes, FR

Key dates

Filing date	Feb 23, 2009
Grant date	Mar 5, 2013
Priority date	—
Expiry date	Nov 11, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/6561
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A system and method for acquiring MR imaging data from a subject includes administering positively-charged nitroxides or gadolinium chelates for in vivo mitochondrial labeling, acquiring MR imaging data from the subject, and reconstructing an image of the subject having enhanced contrast in areas including metabolic and/or mitotic activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.