Compositions and methods for increasing muscle growth

US8388968B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Catrin Berger · Germering, DE
• Tanja Herrmann · Munich, DE
• Chris Lu · Shanghai, CN
• Kelly-Ann Sheppard · Walpole, US
• Estelle Trifilieff · Dietwiller, FR
• Stefanie Urlinger · Munich, DE

Key dates

• Filing date: Apr 26, 2010
• Grant date: Mar 5, 2013
• Expiry date: Nov 16, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This disclosure is in the field of anti-Activin receptor IIB (ActRIIB) antibodies. In particular, it relates to the use of said antibodies for treating muscle disorders, such as muscle wasting due to disease or disuse.