Biological indicator
US8389208B2 · kind B2 · utility
7Cited by
4References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 22, 2005 |
| Grant date | Mar 5, 2013 |
| Priority date | — |
| Expiry date | Aug 16, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/22
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A kinase is used in a biological indicator for validation of treatment processes designed to reduce the amount or activity of a biological agent in a sample. The indication can be used for validation of sterilization treatment. The formation of ATP from a substrate comprising ADP is measured via the liciferin/luciferate system in a luminameter. Thermostable adenylate kinase from sulfolobus acidocaldarius is especially suitable for the validation of procedures to inactivate transmissible spongiform encephalopathy agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.