Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids
US8389226B2 · kind B2 · utility
8Cited by
20References
6Claims
0Family size
Inventors
Key dates
| Filing date | Feb 18, 2011 |
| Grant date | Mar 5, 2013 |
| Priority date | — |
| Expiry date | Feb 18, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/60
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The inventors have discovered a collection of proteinaceous biomarkers (“AD biomarkers) which can be measured in peripheral biological fluid samples to aid in the diagnosis of neurodegenerative disorders, particularly Alzheimer's disease and mild cognitive impairment (MCI). The invention further provides methods of identifying candidate agents for the treatment of Alzheimer's disease by testing prospective agents for activity in modulating AD biomarker levels.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.