Yeast strain for production of four carbon alcohols
US8389252B2 · kind B2 · utility
37Cited by
3References
13Claims
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Key dates
| Filing date | May 5, 2009 |
| Grant date | Mar 5, 2013 |
| Priority date | — |
| Expiry date | May 14, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Yeast cells with a reduced general control response to amino acid starvation were found to have increased tolerance to butanol in the growth medium. The reduced response was engineered by genetic modification of a gene involved in the response, a GCN gene, to eliminate activity of the encoded protein. Yeast strains with an engineered butanol biosynthetic pathway and a genetic modification in a gene involved in the general control response to amino acid starvation, which have increased butanol tolerance, are useful for production of butanol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.