Composition for improving efficiency of drug delivery
US8391959B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 29, 2005 |
| Grant date | Mar 5, 2013 |
| Priority date | — |
| Expiry date | May 6, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/44
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Method and composition suitable for administering by direct convective interstitial infusion are disclosed. The method comprises: placing at least one direct convective interstitial infusion catheter in contact with the tissue, and pressuring the composition through the catheter. The composition is in a liquefied form having a viscosity above a predetermined value. The predetermined value is selected so as to improve infusion of the compositions into interstitial volumes of the tissue, while minimizing backflow of the compositions along an outer wall of the catheter or leakage into low resistance paths. It is demonstrated that high viscosity results in higher treatment efficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.