Papillomavirus pseudoviruses for detection and therapy of tumors

US8394411B2 · kind B2 · utility

Assignee

• THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH · US

Inventors

• Jeff Roberts · Rockville, US
• Douglas R. Lowy · Washington, US
• John T. Schiller · Silver Spring, US

Key dates

• Filing date: May 1, 2008
• Grant date: Mar 12, 2013
• Expiry date: Apr 10, 2029

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/025
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP).