Capture agents and related methods and systems for detecting and/or sorting targets

US8394590B2 · kind B2 · utility

Assignees

• CALIFORNIA INSTITUTE OF TECHNOLOGY · US
• The Regents of the University of California · US

Inventors

• Gabriel A. Kwong · Boston, US
• Caius G. Radu · Los Angeles, US
• Owen N. Witte · West Hollywood, US
• James R. Heath · South Pasadena, US
• Antoni Ribas · Los Angeles, US

Key dates

• Filing date: Oct 8, 2010
• Grant date: Mar 12, 2013
• Expiry date: Oct 8, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/54306
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Polynucleotide-encoded capture agents for target detection and in particular modular polynucleotide-capture agents comprising a target binding component, a scaffold component and an encoding component formed by standardized molecular units that can be coupled and decoupled in a controlled fashion, and related compositions methods and systems.