Lab-on-a-pipette
US8394625B2 · kind B2 · utility
Inventors
Key dates
| Filing date | May 2, 2011 |
| Grant date | Mar 12, 2013 |
| Priority date | — |
| Expiry date | May 2, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01Q70/06
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention generally relates to an integrated ‘lab-on-a-Pipette’™ which will provide sample-to-answer single cell genetic diagnosis for preimplantation genetic diagnosis (PGD) and other forms of single cell analysis (SCA). SCA is a quickly growing field with substantial impact in prenatal testing, cancer biopsies, diabetes, stem cell research, and our overall understanding of heterogeneity in biology. However, single cell genetic analysis is challenging, inaccurate, and in many cases impossible, due to the small amount of sample (5 pg), and difficulties in handling small sample volumes (50-100 pL). The ‘lab-on-a-pipette’ device integrates a microaspiration tip with microfluidic analysis components to conduct in-situ, real-time single cell genetic diagnosis in a single device. The microaspiration tip extracts and encapsulate a cell into an ultra-low volume plug (˜300 pL).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.