Patent · US Active

Biomarkers for renal disease

US8394639B2 · kind B2 · utility

0Cited by

1References

11Claims

0Family size

Assignee

GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN · DE

Inventors

Hassan Dihazi · Oebisfelde, DE
Gerhard Müller · Krefeld, DE
Frank Strutz · Pine Township, US

Key dates

Filing date	Jul 16, 2009
Grant date	Mar 12, 2013
Priority date	—
Expiry date	Mar 21, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/24
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention provides methods and kits for diagnosing a renal disease in a patient or for predicting the risk of a patient for developing a renal disease. In one embodiment, the invention provides a method for diagnosing a renal disease in a patient, comprising determining the level of a ubiquitin fragment having a mass-to-charge ratio (m/z) of 6188 (ubiquitin m/z 6188), or the level of a nucleic acid encoding ubiquitin m/z 6188, in a sample derived from said patient, wherein the substantial absence or a reduced level of less than 25% of ubiquitin m/z 6188 or the nucleic acid encoding ubiquitin m/z 6188 compared to a control is indicative of the renal disease in said patient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.