Use of ursolic acid saponin,oleanolic acid saponin in preparation of increasing leucocytes and/or platelet medicine
US8394776B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Jan 16, 2008 |
| Grant date | Mar 12, 2013 |
| Priority date | — |
| Expiry date | Mar 31, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides the use of ursolic acid saponin and oleanolic acid saponin of formula (I) in preparing medicaments for increasing leucocytes and/or platelets. The invention also provides a pharmaceutical composition containing the same compound. The invention utilizes the cheap and accessible ursolic acid and oleanolic acid which are widely present in natural plants as raw materials, introduces monosaccharyls or oligosaccharyls by structural modification. It is proved by pharmacological tests that the compound of formula (I) have an activity of obviously increasing leucocytes and/or platelets.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.