Hydrazide compounds as thyroid hormone receptor modulators and uses thereof
US8394811B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Apr 18, 2008 |
| Grant date | Mar 12, 2013 |
| Priority date | — |
| Expiry date | Apr 7, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/70
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant thyroid hormone activity, such as hyperthyroidism and thyrotoxicosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.