Patent · US Active

Method of inducing immune tolerance to type I diabetes

US8398995B2 · kind B2 · utility

3Cited by

0References

23Claims

0Family size

Assignee

ACTOGENIX N.V. · BE

Inventors

Pieter Rottiers · Zevergem, BE
Veerle Snoeck · Zingem, BE

Key dates

Filing date	Oct 9, 2009
Grant date	Mar 19, 2013
Priority date	—
Expiry date	Mar 11, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/577
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method for inducing immune tolerance to type I diabetes in a mammal by mucosal delivery of an antigen involved in the induction of type I diabetes such as pro-insulin or insulin is disclosed. The antigen involved in the induction of type I diabetes is delivered together with an IL-10 secreting micro-organism such as Lactococcus lactis and a anti-CD3 antibody.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.