Heteropolynucleotide duplexes with purine—purine base pairing
US8399194B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Dec 21, 2007 |
| Grant date | Mar 19, 2013 |
| Priority date | — |
| Expiry date | Aug 18, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6827
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to stable anti-parallel heteropolynucleotide duplexes, comprising a plurality of complementary purine-purine nucleobase dyads, wherein the nucleobase is coupled to a pentose sugar backbone. The present invention further relates to methods of hybridizing two heteropolynucleotide molecules to form such purine-purine nucleobase dyads, as well as kits and solid supports comprising such purine-purine nucleobase dyads.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.