Device and method for separation, concentration, and/or purification of cells
US8399205B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 20, 2009 |
| Grant date | Mar 19, 2013 |
| Priority date | — |
| Expiry date | Jan 3, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M47/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive property with the particular cell type. The molecules can be directly coated on the surface or coated on nanoparticles that are adhered to the surface. This technology is adaptable for use in implantable shunts and devices for cell trafficking or tumor neutralization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.