Compounds for the treatment of proliferative disorders
US8399435B2 · kind B2 · utility
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5References
10Claims
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Assignee
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Key dates
| Filing date | Oct 7, 2011 |
| Grant date | Mar 19, 2013 |
| Priority date | — |
| Expiry date | Oct 7, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65586
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds of structural formula (I):or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.