Treatment for multiple sclerosis
US8399514B2 · kind B2 · utility
80Cited by
36References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 13, 2012 |
| Grant date | Mar 19, 2013 |
| Priority date | — |
| Expiry date | Feb 13, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/285
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are certain methods of screening, identifying, and evaluating neuroprotective compounds useful for treatment of neurological diseases, such as, e.g., multiple sclerosis (MS). The compounds described upregulate the cellular cytoprotective pathway regulated by Nrf2. Also provided are certain methods of utilizing such compounds in therapy for neurological disease, particularly, for slowing or reducing demyelination, axonal loss, or neuronal and oligodendrocyte death.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.