Process for the manufacture of dabigatran etexilate

US8399678B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Frieder Gnad · Bad Kreuznach, DE
• Stefan Schmitt · Badenheim, DE
• Hermann Mueller-Boetticher · Ober-Hilbersheim, DE
• Helmut Heitger · Ingelheim am Rhein, DE
• Siegfried Meineck · Ober-Hilbersheim, DE
• Rolf Dach · Gau-Algesheim, DE
• Ingo Heddesheimer · Monzingen, DE

Key dates

• Filing date: Nov 4, 2010
• Grant date: Mar 19, 2013
• Expiry date: Jun 4, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C303/32
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An improved process for preparing dabigatran etexilate, as well as analogous compounds of formula 7,is described.