Methods of identifying modulators of GPR17

US8404436B1 · kind B1 · utility

Assignee

• Rheinische Friedrich-Wilhems-Universitaet Bonn · DE

Inventors

• Evi Kostenis · Bonn, DE
• Andreas Spinrath · Munich, DE
• Stephanie Hennen · Aachen, DE
• Lucas Peters · Palmdale, US
• Christa E. Müller · Bonn, DE
• Rhalid Akkari · Pantin, FR
• Younis Baqi · Bonn, DE
• Kirsten Ritter · Jena, DE

Key dates

• Filing date: Feb 28, 2012
• Grant date: Mar 26, 2013
• Expiry date: Feb 28, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/2871
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention is related to a method of determining a test compound's ability to modify the biological activity of a GPR17. Said method comprises, among others, the step of contacting the test compound with a GPR17, or a functional GPR17 fragment in the presence of a suitable amount of a GPR17 agonist of formula I.