Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use
US8404678B2 · kind B2 · utility
29Cited by
8References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 19, 2010 |
| Grant date | Mar 26, 2013 |
| Priority date | — |
| Expiry date | Jan 19, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel tomaymicine derivatives comprising a linker. It also relates to the conjugate molecules that comprise one or more of said tomaymicine derivatives covalently linked to a cell binding agent through a linking group that is present on the linker of the tomaymycin derivative. It also relates to the preparation of the tomaymicine derivatives and of the conjugate molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.