Heterocyclic amide compounds useful as kinase inhibitors

US8404689B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Stephen T. Wrobleski · Whitehouse Station, US
• Jagabandhu Das · Mercerville, US
• T. G. Murali Dhar · Newtown, US
• Alaric J. Dyckman · Lawrenceville, US
• John Hynes · Washington Crossing, US
• Katerina Leftheris · Skillman, US
• James Lin · Lawrenceville, US
• Shuqun Lin · Newtown, US

Key dates

• Filing date: Mar 2, 2011
• Grant date: Mar 26, 2013
• Expiry date: Mar 2, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of Formula Iand enantiomers, diastereomers and pharmaceutically-acceptable salts thereof. Also disclosed are pharmaceutical compositions containing compounds of Formula I, and methods of treating conditions associated with the activity of p38 kinase.