Patent · US Active

Quinolinone derivatives as PARP inhibitors

US8404713B2 · kind B2 · utility

7Cited by
15References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 22, 2008
Grant dateMar 26, 2013
Priority date
Expiry dateOct 4, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of formula (I):wherein R1, R2, R3, R4, R5, Z and n have defined meanings, the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary ammonium salts and the stereochemically isomeric forms thereof, and their use for the treatment of PARP-mediated disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.