Hydroxyalkyl starch derivatives and process for their preparation

US8404834B2 · kind B2 · utility

Assignee

• Fresenius Kabi Deutschland GmbH · DE

Inventors

• Frank Hacket · Schongau, DE
• Thomas Hey · Bad Nauheim, DE
• Franziska Hauschild · Bad Nauheim, DE
• Helmut Knoller · Friedberg, DE
• Martin Schimmel · Oberursel, DE
• Klaus Sommermeyer · Rosbach, DE

Key dates

• Filing date: Dec 15, 2008
• Grant date: Mar 26, 2013
• Expiry date: Dec 15, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08B31/125
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a method for the preparation of a hydroxyalkyl starch derivative which comprises reacting hydroxyalkyl starch (HAS) via the optionally oxidized reducing end of the HAS with the amino group M of a crosslinking compound which, apart from the amino group, comprises a specifically protected carbonyl group, namely an acetal group or a ketal group.