Patent · US Active

Assay device comprising serial reaction zones

US8409523B2 · kind B2 · utility

5Cited by
23References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 1, 2010
Grant dateApr 2, 2013
Priority date
Expiry dateFeb 3, 2031

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01L2400/0475
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

An analysis device having at least one sample addition zone, at least one sink, and at least one flow path connecting the at least one sample addition zone and the at least one sink. The at least one flow path includes projections substantially vertical to the surface of the substrate and having a height (H), diameter (D) and reciprocal spacing (t1, t2) such that lateral capillary flow of a liquid sample is achieved. The device includes at least two reaction zones in series, wherein each reaction zone is adapted to facilitating measurement of a response originating from one and the same analyte, and wherein the reaction zones are positioned to allow calculation of the concentration of at least one analyte. Advantages include that a more accurate value can be calculated, variations are reduced, and an estimation of the uncertainty of the response can be calculated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.