Patent · US Active

Radiolabelling methods

US8409547B2 · kind B2 · utility

0Cited by

0References

3Claims

0Family size

Assignee

Hammersmith Imanet Limited · GB

Inventors

Matthias Eberhard Glaser · Norton, GB
Erik Arstad · London, GB

Key dates

Filing date	Jun 25, 2012
Grant date	Apr 2, 2013
Priority date	—
Expiry date	Jun 25, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K1/13
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to radiodiagnostic and radiotherapeutic agents, including biologically active vectors labelled with radionuclides. It further relates to methods and reagents labelling a vector such as a peptide comprising reaction of a compound of formula (I) with a compound of formula (II):R*-L2-C≡N+—O− (II)or,a compound of formula (III) with a compound of formula (IV)in the presence of a Cu (I) catalyst. The resultant labelled conjugates are useful as diagnostic agents, for example, as radiopharmaceuticals more specifically for use in Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) or for radiotherapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.