Solid dispersion formulations and methods of use thereof
US8409560B2 · kind B2 · utility
2Cited by
49References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 12, 2012 |
| Grant date | Apr 2, 2013 |
| Priority date | — |
| Expiry date | Jun 12, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to formulations and methods for increasing the bioavailability of 1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one, 1-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.