Optical sensors based on hybrid aptamer/conjugated polymer complexes
US8409797B2 · kind B2 · utility
3Cited by
1References
26Claims
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Key dates
| Filing date | Jun 3, 2004 |
| Grant date | Apr 2, 2013 |
| Priority date | — |
| Expiry date | Feb 26, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6811
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An optical sensor for detecting a target comprising a singlestranded aptamer complementary to said target, and a water-soluble cationic polythiophene derivative of the following formula: wherein “n” is an integer ranging from 6 to 100, is disclosed. The optical sensor allows for the detection of targets selected from the group consisting of potassium ions, small organic molecules, amino acids, proteins, whole cells and nucleotides. The detection is based on the formation of hybrid anionic aptamer/cationic poly-thiophene complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.