23-substituted bile acids as TGR5 modulators and methods of use thereof
US8410083B2 · kind B2 · utility
3Cited by
13References
19Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 18, 2008 |
| Grant date | Apr 2, 2013 |
| Priority date | — |
| Expiry date | Feb 14, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/0061
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds of Formula A: (A) or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof. The compounds of Formula A are TGR5 modulators useful for the treatment of various diseases, including obesity, insulin sensitivity, inflammation, cholestasis, and bile desaturation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.