Amide compounds, their pharmaceutical compositions, their preparation method and their uses
US8410094B2 · kind B2 · utility
1Cited by
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10Claims
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Key dates
| Filing date | Sep 18, 2009 |
| Grant date | Apr 2, 2013 |
| Priority date | — |
| Expiry date | Sep 18, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention pertains to the field of pharmaceutical chemistry and discloses 8-(3-aminopropyl)-3-exo-8-azabicyclo[3.2.1]octane-3-amino amide compounds represented by formula I, the pharmaceutical compositions, the preparation method and the use thereof. Such compounds or pharmaceutically acceptable salts thereof can be used as an antagonist of CCR5 in preparing medicaments for treating diseases mediated by CCR5, particularly HIV infection, asthma, rheumatoid arthritis, autoimmune diseases and chronic obstructive pulmonary diseases (COPD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.