Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
US8410109B2 · kind B2 · utility
30Cited by
67References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 28, 2006 |
| Grant date | Apr 2, 2013 |
| Priority date | — |
| Expiry date | Sep 10, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to polyphenol-like compounds that are useful for inhibiting VCAM-1 expression, MCP-1 expression and/or SMC proliferation in a mammal. The disclosed compounds are useful for regulating markers of inflammatory conditions, including vascular inflammation, and for treatment and prevention of inflammatory and cardiovascular diseases and related disease states.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.