8-oxy-quinoline derivatives as bradykinin B2 receptor modulators

US8410134B2 · kind B2 · utility

Assignee

• Shire Orphan Therapies GmbH · DE

Inventors

• Christoph Gibson · Munich, DE
• Thomas Tradler · Berlin, DE
• Karsten Schnatbaum · Berlin, DE
• Jochen Pfeifer · Berlin, DE
• Elsa Locardi · Berlin, DE
• Dirk Scharn · Wien, AT
• Matthias Paschke · Berlin, DE
• Ulf Reimer · Berlin, DE
• Uwe Richter · Berlin, DE
• Gerd Hummel · Berlin, DE
• Ulrich Reineke · Berlin, DE

Key dates

• Filing date: Mar 22, 2008
• Grant date: Apr 2, 2013
• Expiry date: Sep 15, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is related to compound of the formula (I): or a pharmacologically acceptable salt, solvate, or hydrate thereof, wherein A is a 6-membered heteroaryl having from 1 to 3 heteroatoms, each independently selected from N or O and the other substituents are defined as in the claims.