Method for treating diseases associated with alterations in cellular integrity using Rho kinase inhibitor compounds
US8410147B2 · kind B2 · utility
28Cited by
0References
9Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 26, 2009 |
| Grant date | Apr 2, 2013 |
| Priority date | — |
| Expiry date | May 6, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to methods of preventing or treating diseases or conditions associated with alterations in cellular integrity including alterations in endothelial permeability, excessive cell proliferation or tissue remodeling. Particularly, this invention is directed to methods of treating diabetic nephropathy, malaria, or cancer. The method comprises identifying a subject in need of the treatment, and administering to the subject an effective amount of a novel rho kinase inhibitor compound to treat the disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.