Thiazolhydrazides for treatment of neurodegenerative diseases

US8410152B2 · kind B2 · utility

Assignees

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US
• Technische Universität Darmstadt · DE
• THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN · IE

Inventors

• Eckhard Mandelkow · Hamburg, DE
• Eva-Maria Mandelkow · Hamburg, DE
• Markus Pickhardt · Hamburg, DE
• Jacek Biernat · Hamburg, DE
• David George Lloyd · Malahide, IE
• Boris Schmidt · Darmstadt, DE
• Gregor Larbig · Gelnhausen, DE

Key dates

• Filing date: Nov 5, 2007
• Grant date: Apr 2, 2013
• Expiry date: Nov 13, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described are compounds having a thiazolhydrazide scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said thiazolhydrazide compounds can be used for prophylaxis and/or treatment of neurodegenerative diseases and conditions.