High-purity texaphyrin metal complexes
US8410263B2 · kind B2 · utility
2Cited by
56References
4Claims
0Family size
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Key dates
| Filing date | Nov 3, 2009 |
| Grant date | Apr 2, 2013 |
| Priority date | — |
| Expiry date | Mar 14, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/003
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are the methods and compositions for the improved synthesis of texaphyrin metal complexes. The improved synthesis results in high-purity compositions of texaphyrin metal complexes in which more than about 98% of the texaphyrin metal complexes in the composition have the same structure and/or the same molecular weight. Further described herein are pharmaceutical compositions comprising such high-purity compositions, and the use of such high-purity compositions in the treatment of cancer and cardiovascular diseases and disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.