Escherichia coli mutants and methods of use thereof
US8414903B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Nov 20, 2007 |
| Grant date | Apr 9, 2013 |
| Priority date | — |
| Expiry date | Nov 20, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods and compositions for production of gram-negative bacterial mutants that are defective in intestinal colonization capacity and sensitive to infection by bacteriophage P1. Thus the present invention provides immunogenic compositions for the prevention or attenuation of food- and water-borne illnesses associated with ingestion of bacteria such as enterohemorrhagic Escherichia coli.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.