Methods for diagnosing interstitial cystitis via nuclear localization of beta-catenin
US8415108B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Nov 5, 2008 |
| Grant date | Apr 9, 2013 |
| Priority date | — |
| Expiry date | Nov 5, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/34
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for diagnosing a pelvic pain disorder that include analyzing samples for increased levels and/or nuclear accumulation of beta-catenin, which indicates presence of the pelvic pain disorder, particularly interstitial cystitis. Therapeutic treatment of a pelvic pain disorder, particularly interstitial cystitis, includes the administration to a patient of an effective amount of an inhibitor of beta-catenin activity. This can be carried out by direct administration of the therapeutic agent or via gene therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.