Patent · US Active

Cardiomyocyte production

US8415155B2 · kind B2 · utility

5Cited by

3References

17Claims

0Family size

Assignee

Cellular Dynamics International, Inc. · US

Inventors

Casey Stankewicz · Madison, US
Matt Riley · Madison, US
Nathaniel Beardsley · Oregon, US
Wen Bo Wang · Waunakee, US
Peter Fuhrken · Madison, US
Steven Kattman · Toronto, CA

Key dates

Filing date	Oct 19, 2010
Grant date	Apr 9, 2013
Priority date	—
Expiry date	Dec 31, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02E60/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.