Patent · US Active

Antibiotic compositions for the treatment of gram negative infections

US8415307B1 · kind B1 · utility

10Cited by
16References
13Claims
0Family size

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Key dates

Filing dateJun 23, 2011
Grant dateApr 9, 2013
Priority date
Expiry dateJun 28, 2031

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/19
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.