Doxycycline metal complex in a solid dosage form
US8415331B2 · kind B2 · utility
3Cited by
44References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 18, 2008 |
| Grant date | Apr 9, 2013 |
| Priority date | — |
| Expiry date | Dec 18, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1688
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a solid dosage form of a doxycycline metal complex. The present invention also includes a process for making a doxycycline metal complex in a solid dosage form. The process comprises the steps of (i) providing an aqueous solution of doxycycline or a physiologically acceptable salt thereof; (ii) admixing a metal salt with the aqueous solution; (iii) admixing a base to increase the pH of the aqueous solution, thereby forming a suspension of doxycycline metal; and (iv) drying the suspension, thereby forming a dry granulation of doxycycline metal complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.