Patent · US Active

Sulfonamide compound

US8415372B2 · kind B2 · utility

6Cited by
9References
38Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 2007
Grant dateApr 9, 2013
Priority date
Expiry dateFeb 27, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound represented by the formula (1) [A represents a nitrogen-containing saturated ring; m represents an integer of 0 to 2; n represents an integer of 1 to 4; G1 represents hydrogen atom, chlorine atom, hydroxyl group, an alkoxy group, or amino group; G2 represents a halogen atom, hydroxyl group, cyano group, carboxy group, an alkyl group, an alkenyl group, and the like; G3 represents hydrogen atom, a halogen atom, hydroxyl group, cyano group, carboxy group, an alkyl group, an alkenyl group, and the like; G4 represents hydroxyl group, or —N(R1)(R2) (R1 and R2 represent hydrogen atom, an alkyl group, an aralkyl group, an alkenyl group, an alkynyl group, or a saturated heterocyclic group); G5 is a substituent on a ring-constituting carbon atom of A, and represents hydrogen atom, fluorine atom, or an alkyl group] or a salt thereof, or a derivative thereof that is a prodrug, which potently inhibits Rho kinase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.