Patent · US Active

Triazole compounds that modulate HSP90 activity

US8415377B2 · kind B2 · utility

38Cited by

29References

19Claims

0Family size

Assignee

Synta Pharmaceuticals Corp. · US

Inventors

Lijun Sun · Harvard, US
Weiwen Ying · Ayer, US
Junghyun Chae · Michuhol-gu, KR
Teresa Przewloka · Tewksbury, US
Shijie Zhang · Nashua, US
Dinesh U. Chimmanamada · Arlington, US
Kevin Foley · Waltham, US
Zhenjian Du · Northborough, US
Hao Li · Brookline, US
David James · Cambridge, US
Howard P. Ng · El Sobrante, US
Zachary Demko · Los Altos, US
Dan Zhou · Shanxi, CN
Shuzhen Qin · Dedham, US

Key dates

Filing date	Sep 9, 2011
Grant date	Apr 9, 2013
Priority date	—
Expiry date	Sep 9, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.