Methods and immunogenic cell preparations for treating antigen-associated diseases
US8420078B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 21, 2006 |
| Grant date | Apr 16, 2013 |
| Priority date | — |
| Expiry date | Apr 20, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting growth of, reducing or eliminating a cell population of a subject in need thereof is disclosed. The method comprises (a) thermally, mechanically and/or chemically damaging antigen-bearing cells which comprise at least one antigen characterizing cells of the cell population, with the proviso that the chemically damaging of the antigen-bearing cells is not predominantly effected using one or more antineoplastic agents, thereby generating immunogenic cells; and (b) introducing in the subject a cell aggregate which comprises the immunogenic cells and added antigen-presenting cells, thereby inducing an immune response for inhibiting growth of, reducing or eliminating the cell population of the subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.