Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
US8420126B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 23, 2012 |
| Grant date | Apr 16, 2013 |
| Priority date | — |
| Expiry date | Apr 23, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.