Humanized antibody and process for preparing same
US8420353B2 · kind B2 · utility
2Cited by
2References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 22, 2003 |
| Grant date | Apr 16, 2013 |
| Priority date | — |
| Expiry date | Dec 20, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A humanized antibody is produced by process comprising the steps of: (a) selecting a specificity determining residue (SDR) of the complementarity determining region (CDR) of murine monoclonal antibody heavy chain and light chain variable regions; and (b) grafting said SDR to at least one of the corresponding amino acid sequences in human antibody variable regions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.