Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
US8420368B2 · kind B2 · utility
4Cited by
4References
2Claims
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Key dates
| Filing date | Feb 10, 2012 |
| Grant date | Apr 16, 2013 |
| Priority date | — |
| Expiry date | Feb 10, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.